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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTY2D1
All Species:
20.61
Human Site:
S349
Identified Species:
37.78
UniProt:
Q68D10
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68D10
NP_919261.2
685
75546
S349
K
K
S
L
S
H
P
S
H
S
R
P
G
P
M
Chimpanzee
Pan troglodytes
XP_508321
684
75407
S349
K
K
S
L
S
H
P
S
H
S
R
P
G
P
M
Rhesus Macaque
Macaca mulatta
XP_001082108
684
75599
S349
K
K
S
P
S
H
P
S
H
S
R
P
G
P
M
Dog
Lupus familis
XP_534086
793
86791
S460
K
K
S
P
P
H
P
S
H
S
R
P
G
P
M
Cat
Felis silvestris
Mouse
Mus musculus
Q68FG3
682
74799
S349
K
P
L
P
S
H
P
S
H
S
K
P
G
P
T
Rat
Rattus norvegicus
XP_002725626
681
74519
S349
K
S
L
S
S
H
P
S
H
S
K
P
G
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517926
644
69600
P307
P
S
E
K
H
T
R
P
A
T
A
K
P
P
A
Chicken
Gallus gallus
XP_421015
633
66869
N304
E
K
G
K
T
S
Q
N
S
S
L
K
S
P
A
Frog
Xenopus laevis
Q6NU13
800
83727
S458
R
S
V
G
A
S
G
S
G
K
P
T
G
A
S
Zebra Danio
Brachydanio rerio
Q6DGN6
629
69420
G311
R
S
N
S
G
S
S
G
A
L
N
S
K
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMP6
581
65683
E270
E
P
V
V
F
E
V
E
K
K
K
E
P
E
R
Honey Bee
Apis mellifera
XP_395689
579
67372
L268
P
I
D
F
T
E
L
L
K
I
A
E
K
K
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793115
639
72247
E302
N
V
P
S
R
S
I
E
K
Q
L
N
R
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
73.6
N.A.
80.5
82.1
N.A.
55.6
47.8
43
42.7
N.A.
28.3
23.2
N.A.
24
Protein Similarity:
100
99.5
98.5
78.8
N.A.
89.9
90.3
N.A.
66.5
58
56.6
58.6
N.A.
44.2
41.6
N.A.
39.8
P-Site Identity:
100
100
93.3
86.6
N.A.
66.6
66.6
N.A.
6.6
20
13.3
0
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
73.3
73.3
N.A.
13.3
40
26.6
13.3
N.A.
20
6.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
16
0
16
0
0
8
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
16
0
8
0
0
16
0
16
0
0
0
16
0
8
0
% E
% Phe:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
8
0
8
8
8
0
0
0
54
0
8
% G
% His:
0
0
0
0
8
47
0
0
47
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
8
0
0
8
0
0
0
0
0
% I
% Lys:
47
39
0
16
0
0
0
0
24
16
24
16
16
8
0
% K
% Leu:
0
0
16
16
0
0
8
8
0
8
16
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% M
% Asn:
8
0
8
0
0
0
0
8
0
0
8
8
0
0
0
% N
% Pro:
16
16
8
24
8
0
47
8
0
0
8
47
16
62
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
8
% Q
% Arg:
16
0
0
0
8
0
8
0
0
0
31
0
8
0
8
% R
% Ser:
0
31
31
24
39
31
8
54
8
54
0
8
8
8
8
% S
% Thr:
0
0
0
0
16
8
0
0
0
8
0
8
0
8
16
% T
% Val:
0
8
16
8
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _